Collagens form the fibrous component of the extracellular matrix in all multi-cellular animals.Collagen type I is the most abundant collagen present in skin, tendons, vasculature, as well as the organic portion of the calcified tissue of bone and teeth.This review focuses on numerous receptors for which collagen acts as a ligand, including integrin
Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells.
New therapies are needed for metastatic breast cancer patients.Oncolytic herpes simplex virus (oHSV) is an exciting therapy being developed for use against aggressive tumors and established metastases.Although oHSV have been demonstrated safe in clinical trials, a lack of sufficient potency has slowed the clinical application of this approach.We ut
Multiple intrinsic and extrinsic drivers influence the quantity and quality components of seed dispersal effectiveness in the rare shrub Lindera subcoriacea.
Information about seed dispersal effectiveness (SDE) for plant species of conservation concern is rarely available Markers to inform management strategies and actions.For Lindera subcoriacea (bog spicebush, Lauraceae), a rare endemic dioecious shrub of the southeastern United States, we examined the influence of two intrinsic and five extrinsic dri
Multi-environment ecogenomics analysis of the cosmopolitan phylum Gemmatimonadota
ABSTRACT Gemmatimonadota is a diverse bacterial phylum commonly Oil found in environments such as soils, rhizospheres, fresh waters, and sediments.So far, the phylum contains just six cultured species (five of them sequenced), which limits our understanding of their diversity and metabolism.Therefore, we analyzed over 400 metagenome-assembled genom